Related Experiment Video
Updated: Jun 4, 2026

Preparation of a Corannulene-functionalized Hexahelicene by Copper(I)-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
Inherently chiral calixarenes: synthesis, optical resolution, chiral recognition and asymmetric catalysis
Shao-Yong Li1, Yao-Wei Xu, Jun-Min Liu
1College of Pharmacy, Tianjin Medical University, Tianjin 300070, China;
Abstract:
Inherently chiral calixarenes, whose chirality is based on the absence of a planar symmetry or an inversion center in the molecules as a whole through the asymmetric array of several achiral groups upon the three-dimensional calix-skeletons, are challenging and attractive chiral molecules, because of their potential in supramolecular chemistry. The synthesis and optical resolution of all varieties of inherently chiral calixarenes are systematically discussed and classified, and their applications in chiral recognition and asymmetric catalysis are thoroughly illustrated in this review.
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