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Updated: Jun 4, 2026

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
Published on: October 30, 2018
N-heterocyclic carbene-catalysed intermolecular Stetter reactions of acetaldehyde
Sun Min Kim1, Ming Yu Jin, Mi Jin Kim
1Department of Energy Science, Sungkyunkwan University, Suwon 440-746, Korea.
Abstract:
A facile method for the intermolecular Stetter reaction of various Michael acceptors with acetaldehyde as a biomimetic acylanion source was realized using N-heterocyclic carbene catalysis. This catalytic system has also been applied to the enantioselective Stetter reaction and resulted in moderate to good enantioselectivities for the corresponding Stetter products.
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