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Updated: Jun 4, 2026

Microbiological Rapid On-Site Evaluation for Pulmonary Infectious Diseases
Published on: March 1, 2024
[Nosocomial sinusitis in an intensive care unit: a microbiological study]
Leonardo Lopes Balsalobre Filho1, Fernando Mirage Jardim Vieira, Renato Stefanini
1Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Universidade Federal de São Paulo, São Paulo.
Unlabelled:
Nosocomial sinusitis is a common complication of patients in ICUs. Its diagnosis is important, and early treatment is required to avoid serious complications such as pneumonia, sepsis, meningitis, and intracranial abscesses.
Aim:
To identify the germs causing sinusitis in ICUs by nasal swabs and maxillary sinus puncture, and to correlate these results.
Methods:
ICU patients with a diagnosis (CT confirmed) of maxillary sinusitis underwent nasal swab and puncture of the sinus to collect material for culture and antibiogram.
Results:
This study evaluated 22 patients. The microbial agent isolated in the swab correlated with the agent in the puncture in 14 of 22 cases (63%). Gram-negative bacteria were the most frequent, as follows: Pseudomonas aeruginosa (29% of punctures), following by Proteus mirabillis (26%) and Acinetobacter baumanni (14%). The resistance index in the antibiogram was high to antibiotics.
Conclusion:
Maxillary sinus puncture of ICU patients with sinusitis appears to be the best method for identifying bacteria; antibiograms demonstrate resistance to therapy. The swab has little diagnostic value; the correlation was 63%. It may be used when sinus puncture is contraindicated.
Insights
Maxillary sinus puncture is the best method for identifying bacteria causing sinusitis in intensive care units (ICUs). Nasal swabs have limited diagnostic value, showing only 63% correlation with puncture results.
Area of Science:
- Infectious Diseases
- Critical Care Medicine
- Microbiology
Context:
- Nosocomial sinusitis is a frequent complication in intensive care unit (ICU) patients.
- Accurate diagnosis and prompt treatment are crucial to prevent severe outcomes like pneumonia, sepsis, and meningitis.
Purpose:
- To identify the causative microorganisms of sinusitis in ICU patients using nasal swabs and maxillary sinus puncture.
- To compare the diagnostic accuracy of nasal swabs versus maxillary sinus puncture for sinusitis in ICUs.
Summary:
- A study involving 22 ICU patients with CT-confirmed maxillary sinusitis compared microbial identification from nasal swabs and maxillary sinus punctures.
- Maxillary sinus puncture yielded a higher diagnostic yield, with Gram-negative bacteria (Pseudomonas aeruginosa, Proteus mirabillis, Acinetobacter baumanni) being most prevalent.
- Antibiotic resistance was notably high, as indicated by antibiogram results.
Impact:
- Maxillary sinus puncture is recommended as the primary diagnostic method for ICU-acquired sinusitis due to its superior accuracy.
- Nasal swabs demonstrated limited utility, correlating with puncture results in only 63% of cases, but may be considered when puncture is contraindicated.
- Findings highlight the significant challenge of antibiotic resistance in ICU-associated sinusitis.
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