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A Patient-Derived Xenograft Model for Venous Malformation
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Published on: June 15, 2020

Venous angiomas.

Sepideh Amin-Hanjani1

  • 1Neuropsychiatric Institute, University of Illinois at Chicago, Room 451 N, 912 South Wood Street (MC 799), Chicago, IL, 60612, USA, hanjani@uic.edu.

Current Treatment Options in Cardiovascular Medicine
|February 23, 2011
PubMed
Summary
This summary is machine-generated.

Developmental venous anomalies (DVAs), also known as venous angiomas, are generally benign brain lesions. Treatments to remove DVAs are unnecessary and potentially harmful, emphasizing the importance of preserving them.

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Area of Science:

  • Neurology
  • Vascular Malformations
  • Neuroradiology

Background:

  • Venous angiomas are now termed developmental venous anomalies (DVAs), considered functional but anomalous cerebral venous channels.
  • Isolated DVAs are typically benign, with minimal association with hemorrhage, seizures, or headaches.
  • Associated vascular malformations can increase hemorrhage risk, necessitating careful evaluation.

Purpose of the Study:

  • To clarify the nature and clinical significance of developmental venous anomalies (DVAs).
  • To provide guidance on the management of DVAs and associated vascular malformations.
  • To emphasize the risks associated with DVA obliteration and recommend appropriate interventions.

Main Methods:

  • Review of current literature and clinical concepts regarding DVAs.
  • Analysis of the risks and benefits of DVA treatments.
  • Evaluation of DVA associations with other vascular malformations and clinical presentations.

Main Results:

  • Isolated DVAs are benign and do not require treatment.
  • Obliteration of DVAs can cause severe complications, including venous congestion, infarction, and cerebral edema.
  • Management should focus on preserving DVAs, even when treating associated malformations.

Conclusions:

  • DVAs are generally benign and do not warrant obliteration.
  • Interventions should preserve DVAs to avoid potential harm.
  • Management strategies should be tailored to individual cases, considering associated conditions and potential complications.