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One-dimensional genome scanning-detection of genomic changes in ovarian carcinoma
1Department of Pathology, Royal University Hospital Saskatoon, Saskatchawan, Canada.
Methods in Molecular Medicine
|February 23, 2011
Abstract:
Genomic changes are a frequent underlying event in many malignancies, including ovarian cancers, and are intrinsic to the process of oncogenesis and tumor progression. Identification of recurrent nonrandom changes that affect specific genomic regions may provide prognostic information or lead to the discovery of new cancer related genes in somatic tissues.
