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Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
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Published on: September 9, 2012

Screening for the factor v leiden mutation

K P Brown1

  • 1Department of Haematology, Addenbrooke's NHS Trust, Cambridge, UK.

Methods in Molecular Medicine
|February 23, 2011
PubMed

Familial clustering of thrombosis suggests that genetic risk factors are important in the pathogenesis of venous thromboembolism. However, until recently, well defined genetic defects such as antithrombin, protein C and protein S deficiencies accounted for less than 10% of patients with thrombosis.

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