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Updated: Jun 4, 2026
Yeast As a Chassis for Developing Functional Assays to Study Human P53
Published on: August 4, 2019
Clinical Protocol for p53 Gene Therapy for Liver Tumors
M D Kelly1, R R Mitry, N A Habib
1Liver Surgery Section, Imperial College School of Medicine, Hammersmith Hospital, London, UK.
Abstract:
This chapter is intended to help other workers with the preparation of human gene therapy proposals. What follows is an abridged version of a protocol describing the use of gene replacement with p53 for liver tumors. This was submitted to the Gene Therapy Advisory Committee (GTAC) of the Department of Health (United Kingdom). This is the first trial to be approved by GTAC for gene therapy of liver tumors in humans.
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