Related Experiment Video
Updated: Jun 4, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
[Dermoscopy--a glimpse into the skin]
1Department of Plastic Surgery, Assaf Harofeh Medical Center, Zerifin, Israel.
Abstract:
The acronym ABCDE, which was originally described to help with clinically discriminating between benign and malignant pigmented skin lesions, represents the key clinical criteria for diagnosing cutaneous malignant melanoma (CMM). The early stage in CMM is sometimes hard to identify for it frequently mimics the characteristics of atypical nevus. It is estimated that clinical diagnosis accuracy in CMM lies somewhere between 50-75%. This warrants the search for better diagnostic tools. During the last decade, and specifically with the advances in dermoscopy, also known as dermatoscopy or epiluminescence microscopy (ELM), there is literally a new depth and dimension to the clinical diagnosis of pigmented skin lesions. What strikes out as its distinct clinical advantage is its ability to differentiate between an atypical nevus--for which follow-up is the preferred clinical choice, and CMM--which warrants surgical treatment at an early stage. This edge dermoscopy process, put together with a digital interface applied in total-body mapping--as practiced in directed centers, may help decrease the number of false positive excisions without an increase in morbidity from CMM.
More Related Videos
09:37Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
06:34SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments
Published on: August 8, 2025
Related Concept Videos
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Reticular Dermis
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Layers of the Epidermis
Stratum Basale
Stratum basale, also known as the stratum germinativum, is the deepest layer of the epidermis. It is composed of a single layer of actively dividing cells called basal cells or basal keratinocytes. These cells constantly undergo cell division to replenish the upper layers of the epidermis. Additionally, melanocytes, which...
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Introduction to the Integumentary System
The skin, which is the primary organ of the integumentary system, consists of three main layers: the epidermis, dermis, and hypodermis (subcutaneous tissue). The epidermis is the...