Related Experiment Video
Updated: Jun 4, 2026

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease
Published on: June 13, 2025
Cerebellar pathology and micturitional disorders: anatomotopographic and functional correlations
Tiziano Zago1, Umberto Pea, Gian Luca Fumagalli
1Urology Department, FBF Hospital, Milan, Italy.
Abstract:
Cerebellar diseases represent about 2-3% of neurologic pathologies; they usually are classified as:--heredodegeneratives--pure cerebellar syndromes. Such diseases--aside from their aetiology--lead, through several evolutive stages, to different micturitional disorders, in most cases represented by hyperreflexic non dyssynergic bladder and urinary incontinence. On the basis of anatomopathological studies, also considering our 16 years long personal series (1992-2008), we were able to establish a relationship between such disorders and specific cerebellum anomalies, mostly of Purkinje network.
Related Concept Videos
The Micturition Reflex
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating urine...
Cerebellum: Anatomical Regions
Cerebellar Structure
Externally, the cerebellum features a highly convoluted surface with numerous folia (narrow ridges) separated by shallow sulci (grooves). The cerebellum is divided into two hemispheres by a thin median structure known as the vermis. The...
Major Somatic Sensory Pathways
Alterations in Muscle Tone ll
Urinary Bladder
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
Indirect Motor Pathways
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...

