Related Experiment Video
Updated: Jun 4, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Dosimetric and clinical review of helical tomotherapy
1Department of Human Oncology, School of Medicine and Public Health, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI, USA. rong@humonc.wisc.edu
Abstract:
As a modality for delivering rotational therapy, helical tomotherapy offers dosimetric advantages by combining a continuously rotating gantry with a binary multileaf collimator. Helical tomotherapy, embodied in the TomoTherapy(®) Hi-Art II(®) system, delivers intensity-modulated fan beams in a helical pattern using binary multileaf collimator leaves while the couch is translated through the gantry. Helical tomotherapy offers the possibility of treating a variety of cases--from simple to complex--with improved target conformality and sensitive structure sparing compared with 3D or conventional static field IMRT plans, thereby allowing biologically effective dose escalation. For precise irradiation and possible treatment adaptation, the fully integrated on-board image-guidance system provides online volumetric images of patient anatomy using 3.5-MV x-ray beams and the xenon computed tomography detector. Several review articles were published before the year 2007 but emphasized the technical aspects of helical tomotherapy. In this article, we review very recent papers and focus on the dosimetric and clinical aspects of helical tomotherapy.
Related Concept Videos
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Radiological Investigation I: X-ray and CT
Imaging Studies III: Computed Tomography
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

