Developmental outcomes among 18-month-old Malawians after a year of complementary feeding with lipid-based nutrient

John C Phuka1, Melissa Gladstone, Kenneth Maleta

  • 1College of Medicine, University of Malawi, Blantyre, Malawi. johnphuka@yahoo.co.uk

Maternal & Child Nutrition
|February 24, 2011
PubMed

Insights

This study compared infant development using lipid-based nutrient supplements versus fortified corn-soy porridge. Both feeding strategies resulted in similar developmental outcomes for Malawian infants by 18 months.

Area of Science:

  • Pediatrics
  • Nutrition Science
  • Developmental Psychology

Background:

  • Infant malnutrition is a significant public health issue in rural Malawi.
  • Complementary feeding strategies are crucial for optimal child development.
  • Assessing the impact of different nutritional supplements on infant development is essential.

Purpose of the Study:

  • To compare the developmental outcomes of 18-month-old infants receiving complementary feeding for one year.
  • To evaluate the efficacy of lipid-based nutrient supplements (FS50, FS25) against micronutrient-fortified corn-soy porridge (Likuni Phala - LP).
  • To identify socio-economic factors associated with developmental outcomes in rural Malawian infants.

Main Methods:

  • A randomized controlled trial involving 163 six-month-old rural Malawian infants.
  • Intervention groups received daily supplementation with FS50, FS25, or LP for 12 months.
  • Griffiths' developmental scores were assessed at 0-2 years; data analyzed using ANOVA and multiple regression.

Main Results:

  • No significant differences in mean mental ages, raw developmental scores, or developmental quotients were observed among the LP, FS50, and FS25 groups at 18 months.
  • Length-for-age z-score gain and maternal education were significantly associated with developmental outcomes (P=0.03 and P=0.04, respectively).

Conclusions:

  • Daily supplementation with lipid-based nutrient supplements or fortified corn-soy flour for 12 months resulted in comparable infant development outcomes at 18 months.
  • Socio-economic factors, including maternal education and nutritional status (length-for-age z-score gain), play a role in infant development.
  • Both tested nutritional interventions appear effective in supporting infant development in this rural Malawian population.

Related Concept Videos

Development of Human Microbiota01:30

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Lipids: Dietary Sources and Requirements01:18

Lipids: Dietary Sources and Requirements

Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ meats, shellfish,...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...