Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Alterations in Muscle Tone ll01:12

Alterations in Muscle Tone ll

Alterations in muscle tone are common manifestations of neurological disorders and reflect dysfunction within different nervous system regions. Spasticity, paratonia, and dystonia represent distinct forms of hypertonia, each with unique mechanisms, clinical features, and diagnostic importance.CharacteristicsSpasticity happens from upper motor neuron lesions and is characterized by velocity-dependent resistance to passive movement. Clinical features include:Exaggerated deep tendon reflexesClonus...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neural decoding from surface high-density EMG signals: influence of anatomy and synchronization on the number of identified motor units.

Journal of neural engineering·2022
Same author

Mathematical relationships between spinal motoneuron properties.

eLife·2022
Same author

Standard intensities of transcranial alternating current stimulation over the motor cortex do not entrain corticospinal inputs to motor neurons.

The Journal of physiology·2022
Same author

Correlation networks of spinal motor neurons that innervate lower limb muscles during a multi-joint isometric task.

The Journal of physiology·2022
Same author

Reducing the Calibration Time in Somatosensory BCI by Using Tactile ERD.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2022
Same author

The control and training of single motor units in isometric tasks are constrained by a common input signal.

eLife·2022

Related Experiment Video

Updated: Jun 4, 2026

Extraction of the EPP Component from the Surface EMG
07:16

Extraction of the EPP Component from the Surface EMG

Published on: December 16, 2009

A model of the surface electromyogram in pathological tremor.

Jakob Lund Dideriksen, Roger M Enoka, Dario Farina

    IEEE Transactions on Bio-Medical Engineering
    |February 24, 2011
    PubMed
    Summary

    This study introduces a new multi-scale model to simulate surface electromyogram (EMG) during pathological tremor. The model accurately replicates experimental data, offering a powerful tool for tremor analysis.

    More Related Videos

    Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke
    09:10

    Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke

    Published on: February 22, 2020

    Corticospinal Excitability Modulation During Action Observation
    12:33

    Corticospinal Excitability Modulation During Action Observation

    Published on: December 31, 2013

    Related Experiment Videos

    Last Updated: Jun 4, 2026

    Extraction of the EPP Component from the Surface EMG
    07:16

    Extraction of the EPP Component from the Surface EMG

    Published on: December 16, 2009

    Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke
    09:10

    Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke

    Published on: February 22, 2020

    Corticospinal Excitability Modulation During Action Observation
    12:33

    Corticospinal Excitability Modulation During Action Observation

    Published on: December 31, 2013

    Area of Science:

    • Biomedical Engineering
    • Neuroscience
    • Computational Modeling

    Background:

    • Pathological tremor significantly impacts motor control and quality of life.
    • Current experimental methods have limitations in fully understanding tremor mechanisms.
    • Surface electromyogram (EMG) is a key indicator of muscle activity during movement.

    Purpose of the Study:

    • To develop a novel multi-scale model for simulating surface EMG during pathological tremor.
    • To integrate motor unit activity, limb kinematics, and neural control signals within a single model.
    • To investigate the influence of voluntary commands, noise, and feedback on tremor generation.

    Main Methods:

    • Developed a multi-scale mathematical model combining motor unit and limb kinematics.
    • Incorporated descending voluntary commands, oscillatory noise, and afferent feedback.
    • Adjusted oscillatory noise to simulate various pathological tremors.
    • Validated simulations against experimental data for EMG, limb velocity, and motor unit activity.

    Main Results:

    • The model successfully simulated surface EMG and individual motor unit activity.
    • Simulations accurately replicated power spectral density of EMG and limb angular velocity.
    • The model reproduced previously reported experimental findings for tremor characteristics.

    Conclusions:

    • The developed multi-scale model is a powerful tool for studying pathological tremor.
    • It enables detailed analysis of surface EMG and motor unit behavior in various tremor conditions.
    • The model offers insights beyond the scope of experimental approaches alone.