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Diagnostic performance of CT findings in differentiation of perforated from nonperforated appendicitis
Wanwarang Suthikeeree1, Lassanun Lertdomrongdej, Apinya Charoensak
1Department of Radiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand. ampwanwarangs@yahoo.com
Insights
Multidetector row computed tomography (MDCT) effectively differentiates perforated from non-perforated appendicitis. Key CT findings like abscess and extraluminal appendicolith show high specificity for perforation, aiding diagnosis.
Area of Science:
- Radiology
- Medical Imaging
- Gastrointestinal Surgery
Background:
- Acute appendicitis is a common surgical emergency.
- Accurate differentiation between perforated and non-perforated appendicitis is crucial for appropriate patient management.
- Computed tomography (CT) is a widely used imaging modality for diagnosing appendicitis.
Purpose of the Study:
- To evaluate the diagnostic performance of multidetector row computed tomography (MDCT) findings in distinguishing perforated from non-perforated appendicitis.
- To determine the accuracy of individual CT findings in this differentiation.
Main Methods:
- Retrospective review of 48 adult patient CT scans with confirmed acute appendicitis.
- Two radiologists assessed CT findings, comparing them with pathological or surgical outcomes.
- Analysis included sensitivity, specificity, and accuracy of various CT indicators.
Main Results:
- CT findings of abscess, extraluminal appendicolith, and extraluminal air demonstrated high specificity (95.24%-100%) for perforated appendicitis.
- Defect in appendiceal wall enhancement showed the highest accuracy.
- Enlarged mesenteric lymph nodes and appendiceal wall enhancement defects had high sensitivity (88.46%-88.88%).
Conclusions:
- MDCT is a valuable tool for differentiating perforated from non-perforated appendicitis.
- Specific CT findings significantly aid in diagnosing appendiceal perforation.
- Combined CT findings offer improved diagnostic accuracy and sensitivity.
Objective:
To assess performance of CT finding in differentiation of perforated from non-perforated appendicitis in Siriraj hospital, Bangkok, Thailand and evaluate accuracy of each finding by using multidetector row computer tomography (MDCT).
Material And Method:
Between June 2006 and May 2009, all adult patients (age more than 15 years) who had a diagnosis of acute appendicitis in Siriraj Hospital that was confirmed by pathology or surgical records and received a CT scan whole abdomen or lower abdomen with contrast administration before surgical or medical treatment were included in this study. The 48 consecutive CTs of whole or lower abdomen examinations were retrospectively reviewed by two radiologists. Sensitivity specificity, and accuracy of CT compared with pathologic or surgical findings.
Results:
In 48 patients, 21 patients of non-perforated appendicitis and 27 patients of perforated appendicitis were enrolled. The CT findings of abscess, extraluminal appendicolith, and extraluminal air had the highest specificities for perforated appendicitis, 95.24%, 100%, 95.24%, respectively. The best accurate finding was defect in enhancing appendiceal wall. The CT findings of enlarged mesenteric lymph nodes at right lower quadrant region and defect in enhancing appendiceal wall had the highest sensitivities, 88.88% and 88.46%, respectively. Group 3 of combined specific findings had the best sensitivity (92.59%) and accuracy (83.3%).
Conclusion:
Multi-detector CT can help to differentiate perforated from non-perforated appendicitis.
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