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Related Experiment Video

Updated: Jun 4, 2026

Virtual Prism Adaptation Therapy: Protocol for Validation in Healthy Adults

Virtual Prism Adaptation Therapy: Protocol for Validation in Healthy Adults

Published on: February 12, 2020

What on earth is APRV?

Dietrich Henzler¹

¹Department of Anaesthesiology and Division of Critical Care, Queen Elisabeth II Health Sciences Centre, 10 West Victoria, 1276 South Park St, Halifax, NS, B3 H 2Y9, Canada. mail@d-henzler.de

Critical Care (London, England)

|February 25, 2011

Summary

This summary is machine-generated.

Ventilator support definitions are unclear, hindering research. New classifications are needed for accurate mechanical ventilation studies, especially for modes like airway pressure release ventilation (APRV).

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Last Updated: Jun 4, 2026

Virtual Prism Adaptation Therapy: Protocol for Validation in Healthy Adults

Virtual Prism Adaptation Therapy: Protocol for Validation in Healthy Adults

Published on: February 12, 2020

Area of Science:

Critical Care Medicine
Respiratory Physiology
Mechanical Ventilation

Background:

Partial ventilatory support (PVS) modes lack standardized definitions, leading to regional variations in understanding and application.
Recent studies on airway pressure release ventilation (APRV) highlight ambiguities in PVS terminology.
Inconsistent definitions impede the comparability and interpretation of research findings in mechanical ventilation.

Purpose of the Study:

To investigate the feasibility of conducting research on mechanical ventilation modes given current definitional ambiguities.
To critically evaluate the impact of imprecise definitions on studies of partial ventilatory support, using APRV as an example.
To advocate for the development of a standardized taxonomy for ventilation modes.

Main Methods:

Review of recent publications on airway pressure release ventilation (APRV) in adult intensive care unit (ICU) populations.
Analysis of the clarity and precision of definitions used for partial ventilatory support modalities in the cited studies.
Conceptual argument for the necessity of a new classification system for mechanical ventilation.

Main Results:

Current definitions for partial ventilatory support modes are inadequate for precise research.
Lack of clear definitions obscures how patients were ventilated and the extent of spontaneous breathing.
Existing research, even on APRV, yields inconclusive results due to definitional issues.

Conclusions:

Precise definitions are essential for meaningful conclusions in mechanical ventilation research.
The current lack of a standardized taxonomy hinders scientific progress in understanding PVS.
A new, universally accepted taxonomy for ventilation modes is urgently required to improve research quality and clinical practice.