Consensus building and recommendations based on the available epidemiology of meningococcal disease in Gulf Cooperation Council States
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1Ministry of Health, Preventive Medicine Directorate, P.O. Box 54146, Riyadh 11514, Saudi Arabia. zmemish@yahoo.com
Abstract:
The Gulf Cooperation Council (GCC) States share concerns about meningococcal disease, particularly in association with the Hajj and Umrah pilgrimages, which have been connected with outbreaks within the Kingdom of Saudi Arabia and among contacts of the pilgrims in their countries of origin. Currently, the most prevalent meningococcal serogroup in the GCC States is W-135. Although vaccination with polysaccharide vaccines has protected pilgrims and their close contacts from invasive disease, the potential availability of novel conjugate vaccines, such as the one currently used for vaccination of military personnel in the Kingdom of Saudi Arabia, prompted an evaluation of disease epidemiology in the region. For several countries, published data on recent epidemiology are not available. We report findings from a meeting of the GCC States Meningitis Study Group, which comprised experts from the Kingdom of Saudi Arabia, the Kingdom of Bahrain, Kuwait, Qatar, the Sultanate of Oman, and the United Arab Emirates. These experts provided an update on epidemiology and current vaccination practices in the GCC States, and discussed new approaches to more effective disease prevention.
Insights
Meningococcal disease, especially serogroup W-135, is a concern in Gulf Cooperation Council (GCC) States, particularly during Hajj and Umrah pilgrimages. Experts discussed epidemiology and new conjugate vaccines for better prevention.
Area of Science:
- Public Health
- Epidemiology
- Vaccinology
Background:
- Meningococcal disease poses a significant risk in Gulf Cooperation Council (GCC) States, exacerbated by Hajj and Umrah pilgrimages.
- Serogroup W-135 is currently the most prevalent cause of meningococcal disease in the GCC region.
- Previous outbreaks have been linked to pilgrimages and spread among travelers and their contacts.
Purpose of the Study:
- To update the understanding of meningococcal disease epidemiology in GCC States.
- To review current vaccination practices for meningococcal disease prevention in the region.
- To explore the potential of novel conjugate vaccines for enhanced disease control.
Main Methods:
- Convened a meeting of the GCC States Meningitis Study Group, including experts from Saudi Arabia, Bahrain, Kuwait, Qatar, Oman, and UAE.
- Experts provided updated epidemiological data and information on current vaccination strategies.
- Discussion focused on emerging trends and future prevention approaches.
Main Results:
- The most prevalent meningococcal serogroup in GCC States is W-135.
- Polysaccharide vaccines have offered protection, but novel conjugate vaccines are under consideration.
- Recent epidemiological data for some countries were not readily available prior to this meeting.
Conclusions:
- Continued surveillance and updated epidemiological data are crucial for effective meningococcal disease control in GCC States.
- Novel conjugate vaccines represent a promising avenue for improving prevention strategies.
- Collaborative efforts among GCC nations are essential for addressing the burden of meningococcal disease.
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