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Related Experiment Video

Updated: Jun 4, 2026

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
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Published on: March 13, 2018

CHIKVPRO - a protein sequence annotation database for chikungunya virus.

Akaash Kumar Mishra1, Chakresh Kumar Jain, Apurva Agrawal

  • 1Department of Biotechnology, Jaypee Institute of Information Technology, NOIDA 201307, India.

Bioinformation
|February 25, 2011
PubMed
Summary
This summary is machine-generated.

Chikungunya virus (CHIKV) outbreaks have increased interest in CHIKV. A new database, CHIKVPRO, offers structural and functional annotations for CHIKV proteins from 25 strains, aiding virology research.

Keywords:
CHIKVCHIKVPROChikungunya virusdatabaseprotein sequence

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Area of Science:

  • Virology
  • Bioinformatics
  • Genomics

Background:

  • Resurgence of Chikungunya virus (CHIKV) interest due to widespread outbreaks in South-East Asia.
  • Increased submission of CHIKV genome sequences to the National Center for Biotechnology Information (NCBI) database.

Purpose of the Study:

  • To introduce CHIKVPRO, a novel database resource for Chikungunya virus proteome.
  • To provide comprehensive structural and functional annotations for CHIKV proteins.

Main Methods:

  • Curated CHIKV protein data from 25 strains submitted to NCBI.
  • Utilized Expasy tools and SVMProt for protein classification and functional family assignment.
  • Included analysis of physiochemical properties, hydrophobicity, and transmembrane predictions.

Main Results:

  • CHIKVPRO database contains annotations for all 9 CHIKV proteins (4 non-structural, 5 structural).
  • Database provides detailed molecular and physiochemical properties, cleavage sites, and functional classifications.
  • Offers a centralized resource for CHIKV proteome information.

Conclusions:

  • CHIKVPRO serves as an authoritative, single-access point for CHIKV proteome data.
  • The database facilitates further research into CHIKV structure, function, and pathogenesis.
  • Accessible online at http://www.chikvpro.info/ for the scientific community.