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Evaluation of RxNorm for Representing Ambulatory Prescriptions
Sean M O'Neill1, Douglas S Bell
1RAND Corporation, Santa Monica, CA;
AMIA ... Annual Symposium Proceedings. AMIA Symposium
|February 25, 2011
Summary
RxNorm effectively represents ambulatory electronic prescriptions, showing high coverage and consistent concept mapping. Minor improvements are suggested for concept specificity in this drug nomenclature system.
Area of Science:
- Health Informatics
- Pharmacology
- Clinical Drug Data Standards
Background:
- Electronic prescribing systems generate vast amounts of drug data.
- Standardized drug nomenclature is crucial for data interoperability and analysis.
- RxNorm is a standard for drug nomenclature in the United States.
Purpose of the Study:
- To evaluate the RxNorm standardized drug nomenclature for representing ambulatory electronic prescriptions.
- To assess the coverage, stability, and consistency of RxNorm concepts for e-prescriptions.
Main Methods:
- Analyzed 19,743 primary care e-prescriptions.
- Estimated RxNorm coverage and 6-month concept replacement rates.
- Assessed consistency of independent concept mappings and investigated discrepancies.
Main Results:
- RxNorm demonstrated 99.995% coverage for clinical drugs in e-prescriptions.
- 8.1% of RxNorm concepts were replaced over a 6-month period.
- 3.4% of mappings showed minor inconsistencies, with low clinical significance.
Conclusions:
- RxNorm provides comprehensive coverage for ambulatory e-prescriptions.
- Independent mappings using RxNorm are relatively consistent.
- Enhancements in concept specificity selection could further optimize RxNorm's utility.
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