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Comparing the effectiveness of a clinical registry and a clinical data warehouse for supporting clinical trial
Chunhua Weng1, J Thomas Bigger, Linda Busacca
1Department of Biomedical Informatics;
Abstract:
This paper reports a case study comparing the relative efficiency of using a Diabetes Registry or a Clinical Data Warehouse to recruit participants for a diabetes clinical trial, TECOS. The Clinical Data Warehouse generated higher positive predictive accuracy (31% vs. 6.6%) and higher participant recruitment than the Registry (30 vs. 14 participants) in a shorter time period (59 vs. 74 working days). We identify important factors that increase clinical trial recruitment efficiency and lower cost.
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