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Pyrenochaeta romeroi: a causative agent of phaeohyphomycotic cyst
Ziauddin Khan1, Suhail Ahmad1, Kusum Kapila2
1Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait.
Abstract:
A subcutaneous phaeohyphomycotic cyst caused by Pyrenochaeta romeroi in a 47-year-old Indian female is described. The organism was isolated repeatedly from the aspirated material from the cyst. It was identified by colony and microscopic characteristics, and sequencing of internal transcribed spacer regions of the rDNA. Although the patient recovered without antifungal therapy, the isolate appeared resistant to commonly used antifungal agents. To the best of our knowledge, this is only the second report of subcutaneous phaeohyphomycotic cyst caused by Pyrenochaeta romeroi.
Insights
A rare subcutaneous phaeohyphomycotic cyst caused by Pyrenochaeta romeroi was identified in an Indian female. The Pyrenochaeta romeroi isolate showed antifungal resistance, despite the patient
Area of Science:
- Medical Mycology
- Infectious Diseases
- Dermatology
Background:
- Phaeohyphomycosis is a fungal infection caused by dematiaceous fungi.
- Subcutaneous phaeohyphomycotic cysts are rare clinical manifestations.
Observation:
- A 47-year-old Indian female presented with a subcutaneous cyst.
- Pyrenochaeta romeroi was repeatedly isolated from cyst aspirates.
- Identification confirmed by morphology and rDNA sequencing.
Findings:
- The Pyrenochaeta romeroi isolate exhibited resistance to common antifungal agents.
- The patient recovered spontaneously without antifungal treatment.
- This is the second reported case of subcutaneous phaeohyphomycosis caused by Pyrenochaeta romeroi.
Implications:
- Highlights the potential for Pyrenochaeta romeroi to cause subcutaneous infections.
- Suggests that antifungal resistance may be a feature of Pyrenochaeta romeroi.
- Emphasizes the importance of accurate fungal identification in clinical practice.
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