Pyrenochaeta romeroi: a causative agent of phaeohyphomycotic cyst

Ziauddin Khan1, Suhail Ahmad1, Kusum Kapila2

  • 1Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait.

Insights

A rare subcutaneous phaeohyphomycotic cyst caused by Pyrenochaeta romeroi was identified in an Indian female. The Pyrenochaeta romeroi isolate showed antifungal resistance, despite the patient

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Dermatology

Background:

  • Phaeohyphomycosis is a fungal infection caused by dematiaceous fungi.
  • Subcutaneous phaeohyphomycotic cysts are rare clinical manifestations.

Observation:

  • A 47-year-old Indian female presented with a subcutaneous cyst.
  • Pyrenochaeta romeroi was repeatedly isolated from cyst aspirates.
  • Identification confirmed by morphology and rDNA sequencing.

Findings:

  • The Pyrenochaeta romeroi isolate exhibited resistance to common antifungal agents.
  • The patient recovered spontaneously without antifungal treatment.
  • This is the second reported case of subcutaneous phaeohyphomycosis caused by Pyrenochaeta romeroi.

Implications:

  • Highlights the potential for Pyrenochaeta romeroi to cause subcutaneous infections.
  • Suggests that antifungal resistance may be a feature of Pyrenochaeta romeroi.
  • Emphasizes the importance of accurate fungal identification in clinical practice.

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