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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
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Tonsillitis II: Management

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Myocarditis IV: Nursing Management

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Related Experiment Video

Updated: Jun 4, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

Management of optic neuritis.

Vimla Menon1, Rohit Saxena, Ruby Misra

  • 1Dr. R. P. Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Indian Journal of Ophthalmology
|February 26, 2011
PubMed
Summary

Optic neuritis, an inflammatory optic nerve condition, often affects young women. While multiple sclerosis is a common cause, other factors exist, and treatment effectiveness varies by region.

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Immunology

Background:

  • Optic neuritis involves sudden unilateral vision loss, frequently in young females.
  • Demyelination linked to multiple sclerosis (MS) is a primary cause in MS-prevalent regions.
  • Infective or autoimmune etiologies are significant in other geographic areas.

Purpose of the Study:

  • To review the natural history of optic neuritis.
  • To evaluate the role of steroids and the risk of developing MS.
  • To analyze the efficacy of various management strategies for optic neuritis and MS.

Main Methods:

  • Review of landmark clinical trials including the Optic Neuritis Treatment Trial (ONTT).
  • Analysis of data from the CHAMPS, PRISMS, and BENEFIT studies.

Related Experiment Videos

Last Updated: Jun 4, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

  • Examination of treatment outcomes and cost-effectiveness.

    • Main Results:

    • The ONTT established baseline data on optic neuritis' natural course and steroid treatment.
    • Subsequent trials provided extensive information on optic neuritis and MS management.
    • Interferon therapy may not be cost-effective in Asian populations due to low MS prevalence and high costs.

    Conclusions:

    • Optic neuritis management requires consideration of underlying causes and regional prevalence.
    • While effective treatments exist, their cost-effectiveness varies globally.
    • Further research may be needed to optimize treatment strategies in diverse populations.