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Related Experiment Video

Updated: Jun 4, 2026

2D-HPLC-MS Technology Combined with Molecular Network for the Identification of Components in Tibetan Medicine Aconitum pendulum
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[Two new compounds from Psoralea corylifolia L].

Tong-Tong Yang1, Jing Li, Min-Jian Qin

  • 1School of Pharmacy, Jiangsu University, Zhenjiang 212013, China.

Yao Xue Xue Bao = Acta Pharmaceutica Sinica
|March 1, 2011
PubMed
Summary

Two novel chemical compounds, coryfolia D and bavarigenin, were identified from Psoralea corylifolia L. fruits. These compounds were isolated and characterized using advanced spectroscopic techniques.

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Area of Science:

  • Phytochemistry
  • Natural Product Chemistry
  • Organic Chemistry

Context:

  • Psoralea corylifolia L. is a traditional medicinal plant.
  • Investigating the chemical profile of medicinal plants is crucial for discovering bioactive compounds.
  • Chromatographic and spectroscopic methods are standard for natural product isolation and characterization.

Purpose:

  • To isolate and identify new chemical constituents from Psoralea corylifolia L. fruits.
  • To elucidate the structures of these novel compounds using spectroscopic data.

Summary:

  • Two new compounds, coryfolia D and bavarigenin, were successfully isolated from the ethyl acetate-soluble fraction of Psoralea corylifolia L. fruit extract.
  • Compound 1, 2-(3,4-dihydroxyphenyl)-8,8-dimethyl-8H-pyrano[2,3-h]chromen-4-one, was named coryfolia D.

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Last Updated: Jun 4, 2026

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  • Compound 2, 5-(2-hydroxyl-1-methyl)-ethyl-4,5-dihydrofurano[2,3-h](4'-hydroxyl-3',5'-dimethoxy)-isoflavone, was named bavarigenin.
  • Structural determination was achieved through comprehensive 1D and 2D NMR spectroscopy.

    • Impact:

    • Expansion of the known chemical diversity of Psoralea corylifolia.
    • Provides novel compounds for potential future pharmacological investigations.
    • Contributes to the understanding of the phytochemical composition of this medicinal plant.