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Related Experiment Videos

The antibacterial effect of SPAD.

M M Negm1, M A Kataia

  • 1Department of Endodontics, Cairo University.

Egyptian Dental Journal
|January 1, 1990
PubMed
Summary

SPAD, a root canal paste, demonstrated significant antibacterial effects against streptococci group D. Calcium hydroxide paste showed no antibacterial activity in this study.

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Area of Science:

  • Endodontics
  • Microbiology
  • Dental Materials Science

Background:

  • Root canal infections often involve bacteria like Streptococcus group D.
  • Effective antibacterial agents are crucial for successful root canal therapy.
  • Paraformaldehyde-based pastes are used for obturation, while calcium hydroxide is used for apexification.

Purpose of the Study:

  • To compare the antibacterial efficacy of SPAD (a paraformaldehyde-based obturation paste) with calcium hydroxide apexification paste.
  • To evaluate the antibacterial activity over time.
  • To assess the inhibition of Streptococcus group D growth.

Main Methods:

  • In vitro study comparing SPAD and calcium hydroxide paste.
  • Materials placed in cultures with Streptococcus group D isolated from infected root canals.
  • Antibacterial effect evaluated by measuring bacterial inhibition zones at 3, 7, and 15 days.
  • Incubation periods of 24, 48, and 27 hours for zone measurement.

Main Results:

  • SPAD exhibited wide bacterial inhibition zones, indicating strong antibacterial activity.
  • The antibacterial effect of SPAD diminished over time as formaldehyde release decreased.
  • Calcium hydroxide paste demonstrated no significant antibacterial effect throughout the study period.

Conclusions:

  • SPAD possesses potent, albeit time-dependent, antibacterial properties against Streptococcus group D.
  • Calcium hydroxide paste lacks significant antibacterial efficacy in this experimental model.
  • SPAD may be a more effective option for managing bacterial contamination in root canals compared to calcium hydroxide.

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