Related Experiment Video
Updated: Jun 4, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
Biodiversity and Lyme disease: dilution or amplification?
1Centre for Foodborne, Environmental and Zoonotic Infectious Diseases, Public Health Agency of Canada/Agence de la santé publique du Canada, 3200 Sicotte, Saint-Hyacinthe, Québec, Canada.
Abstract:
Reduced Lyme disease risk by the 'dilution effect' is often cited as an example of biodiversity providing 'ecosystem services' to public health. Using a mechanistic model we investigated how transmission of the Lyme disease agent, Borrelia burgdorferi, by Ixodes scapularis ticks amongst highly efficient reservoir mice is affected by varying the abundance of a less efficient reservoir host. Simulations indicated either amplification or dilution may occur, with the outcome depending precisely on mechanisms of competition, host contact rates with ticks, and acquired host resistance to ticks. Quantifying these mechanisms will be crucial to predicting how biodiversity affects Lyme disease risk.
Related Concept Videos
Threats to Biodiversity
Dysbiosis of the Gut Microbiota
Applications of Molecular Taxonomy
Gene Regulation in Microbial Communities: Quorum Sensing
Reservoir of Infection
Mutation, Gene Flow, and Genetic Drift

