Surgery for anomalous aortic origin of the coronary artery
Muhammad A Mumtaz1, Richard E Lorber, Janine Arruda
1Children's Cardiothoracic Surgery, Children's Hospital of the King's Daughters, Norfolk, Virginia 23507, USA. ali.mumtaz@chkd.org
Insights
Coronary unroofing is a safe and effective treatment for anomalous aortic origin of the coronary artery (AAOCA) in symptomatic patients. This surgical approach demonstrated no complications in a recent study.
Area of Science:
- Cardiovascular Surgery
- Congenital Heart Disease
- Pediatric Cardiology
Background:
- Anomalous aortic origin of the coronary artery (AAOCA) is linked to serious cardiac events like ischemia and sudden death.
- Advanced imaging techniques aid in identifying patients at risk for AAOCA complications.
- Surgical unroofing is a primary treatment for AAOCA, addressing both symptomatic and asymptomatic cases.
Purpose of the Study:
- To evaluate the safety and efficacy of coronary unroofing for treating anomalous aortic origin of the coronary artery.
- To review surgical outcomes in patients with different types of AAOCA.
- To assess the long-term patency of repaired coronary arteries.
Main Methods:
- Coronary unroofing was performed on 22 patients with AAOCA between 1998 and 2008.
- Patients included those with "left from right" and "right from left" AAOCA origins, presenting with various symptoms.
- Concomitant procedures, such as patent foramen ovale closure, were performed in eight patients.
Main Results:
- No deaths or surgical complications were reported in the study cohort.
- The mean hospital stay was 4 days, with a mean cross-clamp time of 53 minutes.
- Postoperative assessments confirmed the patency of the repaired coronary artery in all patients, with a mean follow-up of 17 months.
Conclusions:
- Coronary unroofing is a safe and effective surgical option for symptomatic patients with anomalous aortic origin of the coronary artery.
- The study highlights the emerging recognition of AAOCA as a distinct clinical entity.
- Further prospective research is needed to clarify surgical indications for asymptomatic patients, particularly differentiating between "left from right" and "right from left" AAOCA.
Background:
Anomalous aortic origin of the coronary artery (AAOCA) has been associated with coronary ischemia, myocardial infarction, and sudden death. Advances in echocardiography and computed tomography have identified at-risk patients. Treatment options include unroofing strategies in symptomatic and asymptomatic patients. We review our experience for efficacy and safety.
Methods:
Between 1998 and 2008, we performed coronary unroofing in 22 patients with AAOCA without aortic commissural detachment. Of 7 patients with "left from right" AAOCA, 4 had chest pain only, 1 had syncope, 1 had myocardial infarction, and 1 was asymptomatic. Of 15 patients with "right from left" AAOCA, 11 had chest pain only, 4 had syncope, and none were without symptoms. Median age was 15 years (range, 5 to 54). Eight patients had concomitant procedures, most commonly patent foramen ovale closure.
Results:
There were no deaths or complications. Mean cross-clamp time was 53 minutes. Mean length of stay was 4 days. Postoperative evaluation included echocardiography, computed tomography angiogram, stress thallium, stress echocardiography, and exercise stress test. In all patients, the repaired coronary was patent, with demonstrated flow. Mean follow-up was 17 months (range, 1 to 63).
Conclusions:
Anomalous aortic origin of the coronary artery is emerging as an identifiable disease entity associated with symptoms or sudden death. We conclude that coronary unroofing is a safe and effective therapy for symptomatic patients. Surgery for asymptomatic patients has been more controversial, with growing advocacy for patients with "left from right" as opposed to "right from left" origins. Prospective studies will be required to answer these questions.
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