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Published on: December 6, 2016
[Obstructive sleep-related respiratory disorders in children]
María Teresa Pascual Sánchez1, Lilian Herrera Velasco, Pilar Arroyo Guijarro
1Departamento de Neumología Infantil, Hospital General de Catalunya, Sant Cugat del Vallès, Barcelona, España. maitepasc@hotmail.com
Insights
Sleep significantly impacts respiratory health, with breathing changes during deep sleep. Sleep-related respiratory disorders worsen during sleep, affecting conditions like sleep apnea-hypopnea syndrome.
Area of Science:
- Physiology
- Respiratory Medicine
- Sleep Science
Context:
- Sleep is vital for health, involving physiological changes affecting respiration.
- Sleep-related respiratory disorders are a significant clinical concern, often underdiagnosed.
- These disorders can manifest exclusively during sleep or exacerbate existing conditions.
Purpose:
- To define and discuss sleep-related respiratory disorders.
- To highlight the physiological changes in ventilation during sleep.
- To underscore the connection between sleep disorders and other health issues.
Summary:
- During deep sleep, ventilation patterns change: tidal volume increases, respiratory rate slows, and inhalation/expiration phases lengthen while maintaining volume/time ratio.
- Sleep-related respiratory disorders encompass conditions like sleep apnea-hypopnea syndrome and congenital central hypoventilation syndrome, which manifest or worsen during sleep.
- These disorders are linked to prevalent conditions such as obesity and gastroesophageal reflux, and can impact cognitive function and learning in children.
Impact:
- Improved understanding of respiratory physiology during sleep.
- Enhanced diagnosis and management of sleep-related breathing disorders.
- Highlights the systemic impact of sleep disturbances on overall health and cognitive processes.
Abstract:
Sleep is a biological mechanism essential to maintaining good health. A series of physiological changes takes place during sleep. From a ventilation point of view, during deep sleep, tidal volume increases, the inhalation and expiration phases become longer, and respiratory frequency slows, while the same volume/time ratio as in wakefulness is maintained. The concept of "sleep-related respiratory disorders" refers to a group of respiratory diseases that are aggravated during sleep. Some of these disorders are almost exclusively manifested during sleep, such as sleep apnea-hypopnea syndrome -undoubtedly the most frequent respiratory disease despite being underdiagnosed- and congenital central hypoventilation syndrome (also called Ondine's curse). However, this concept also encompasses other disorders that occur during the daytime since they worsen while patients are asleep, as seen in many obstructive or restrictive pulmonary diseases. Sleep disorders can be a manifestation of underlying diseases, some of which are highly prevalent such as obesity and gastroesophageal reflux. Likewise, abnormal sleep cycles may be a cause or a result of cognitive disorders and disturbances in children's learning processes.
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