[Experimental studies of healing process on reinforcement ceramic implantation in rabbit mandible]

The following results were obtained from the experiment on the five different blocks (HAP, HAP.diopside, diopside, HAP.anorthite and anorthite) which were created as a material of dental implant for in rabbit mandible. Implantation was done on those five blocks under the same condition using pathologic histology, SEM and TEM to see and examine about the changes in the inner surface of each block, the joint condition of new bone and the block, and new bone created around each block and follow its maturing procedure. 1. Much resorption was not seen HAP block even after 48 weeks, with HAP.diopside block, beta-TCP of HAP was resolved, and with HAP.anorthite block, its inner surface was either broken or resolved. Diopside was resolved only in the inner surface, but it was limited only in the Si-rich area. 2. HAP block was created in the long term, and with HAP.anorthite and anorthite block, their inner surface tended to brake apart. In comparison, neither cracking on parting was seen with diopside and HAP.diopside. 3. In two weeks after operation, direct bone was created and attached to diopside with HAP and HAP.diopside, this kind of bone formation was seen in the part of it, and in the rest of the part, the fiber was created. HAP.anorthite and anorthite did not seem to have new bone attached to the direct block. 4. By 4 weeks after the operation, diopside block was surrounded and stabilized by the completed new bone. It took more than 12 weeks for HAP, HAP.diopside, HAP.anorthite and anorthite block to have osteon in the new bone. 5. Crystal lattice created by HAP crystal which appeared in the diopside block, and apatite crystal in the new bone is continuous and arranged in one direction. 6. From above mentioned study results, we can say that diopside is mechanically strong, and because of new bone created along the block surface at an early stage, it is stabilized in the bone soon after the implantation and is the most suitable as a material of dental implant in all the blocks used in this study case.