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Updated: Jun 4, 2026

Applications of Liquid-Chromatography Tandem Mass Spectrometry in Natural Products Research: Tropane Alkaloids as a Case Study
Published on: March 8, 2024
[Alkaloids of Daphniphyllum angustifolium]
Tao He1, Shuzhen Mu, Xiaojiang Hao
1College of Life Science, Guizhou University, Guiyang 550025, China.
Abstract:
The alkaloids of Daphniphyllum angustifolium were investigated. The whole plant was extracted with 95% EtOH, six alkaloids were isolated and purified with column chromatography over silica gel, RP-18 and Sephadex LH-20. Based on spectral analysis, their structures were identified as daphnilactone B (1), zwitterionic alkaloid (2), yuzurine (3), dehydrodaphnigracilline (4), deoxyyuzurimine (5) and macrodaphniphyllidine (6). All of compounds were obtained from the plant for the first time.
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