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Published on: March 21, 2018

Prenatal management of the fetus with lethal malformation: from a study of oligohydramnios sequence

Hiromi Nagase1, Hiroshi Ishikawa, Tomoko Nishikawa

  • 1Division of Obstetrics and Gynecology, Kanagawa Children's Medical Center, Yokohama, Japan. h-nagase@mtj.biglobe.ne.jp

Fetal and Pediatric Pathology
|March 2, 2011
PubMed

47 cases of oligohydramnios sequence (OS) diagnosed at Kanagawa Children's Medical Center from 1992 to 2008 were studied retrospectively. Early termination of pregnancy was chosen in 9 cases, observed natural labor was chosen in 23 cases, and 18 cases resulted in natural deliveries. Fetal demise occurred during labor in 44.4% of terminated cases, while it occurred in 5.6% of observed cases. Preterm labors and breech presentations occurred most frequently. Most infants died within 18 hours after their births. There were 3 familial cases. These results provide important information for planning the perinatal care when fetuses are diagnosed with OS.

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