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Ten-year risk for myocardial infarction in patients with first-ever stroke: a community-based study

P Appelros1, K E Gunnarsson, A Terént

  • 1Department of Neurology, Örebro University Hospital, Sweden. peter.appelros@orebroll.se

Acta Neurologica Scandinavica
|March 2, 2011
PubMed

Insights

Stroke patients face a significantly higher risk of myocardial infarction (MI) compared to the general population. Previous coronary heart disease (CHD) and peripheral artery disease increase this risk, necessitating thorough secondary prevention.

Area of Science:

  • Cardiovascular Medicine
  • Neurology
  • Public Health

Background:

  • Stroke and coronary heart disease (CHD) share common risk factors.
  • The risk of myocardial infarction (MI) in stroke patients is not well-established.

Purpose of the Study:

  • To investigate the 10-year incidence of MI in first-ever stroke patients.
  • To compare MI risk in stroke patients to the general population.
  • To identify predictors of MI in stroke patients.

Main Methods:

  • Prospective ascertainment of 377 first-ever stroke patients.
  • 10-year MI incidence examined via register searches.
  • Univariate and multivariate analyses to identify MI predictors.

Main Results:

  • The 10-year cumulative incidence of MI was 25.0% in stroke patients.
  • Stroke patients had a 1.6-1.9 times higher relative risk of MI than the general population.
  • Previous CHD and peripheral artery disease were significant MI predictors.

Conclusions:

  • Stroke patients have a significantly elevated risk of MI.
  • Patients with prior CHD or peripheral artery disease face the highest MI risk.
  • Adequate secondary prevention and attention to cardiac symptoms are crucial for stroke survivors.
Abstract

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