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[Influence of aging on respiratory function with emphasis on senile persons]
1Department of Anesthesiology, Nihon University School of Dentistry at Matsudo.
Nichidai Koku Kagaku = Nihon University Journal of Oral Science
|June 1, 1990
Summary
Respiratory function declines with age in older men, with restrictive impairment worsening and obstructive impairment remaining mild. Ventilation issues develop in men over 60, impacting lung function sensitivity.
Area of Science:
- Gerontology and Respiratory Medicine
- Pulmonary Function Testing
- Aging Physiology
Context:
- Aging significantly impacts respiratory function in men over 60.
- Previous studies often lack detailed analysis of specific ventilation impairments in senile populations.
- This study investigates age-related changes in pulmonary function using timed vital capacity and flow-volume curves.
Purpose:
- To analyze the changes in respiratory function in senile males (aged 60-86).
- To differentiate between restrictive and obstructive ventilation impairments with aging.
- To examine the relationship between pulmonary function parameters and age-related ventilation changes.
Summary:
- Forced vital capacity and % FVC decrease with age, while FEV1.0% remains stable.
- Peak flow, V75, and V50 decrease with age, indicating worsening restrictive ventilation.
- Ventilation impairment, particularly restrictive, increases with age in men over 60, with reduced sensitivity to V50/V25.
Impact:
- Highlights the progressive nature of restrictive lung disease in aging men.
- Suggests that while obstructive impairment is mild, restrictive changes significantly affect lung function.
- Provides data for understanding age-related respiratory health and potential interventions.