Related Experiment Video
Updated: Jun 4, 2026

A New Best Practice for Validating Tail Vein Injections in Rat with Near-infrared-Labeled Agents
Published on: April 19, 2019
Visualizing veins with near-infrared light to facilitate blood withdrawal in children
Natascha J Cuper1, Rudolf M Verdaasdonk, Rowland de Roode
1University Medical Center, Utrecht, Netherlands. n.j.cuper@umcutrecht.nl
Introduction:
This study aims to evaluate for the first time the value of visualizing veins by a prototype of a near-infrared (NIR) vascular imaging system for venipuncture in children.
Methods:
An observational feasibility study of venipunctures in children (0-6 years) attending the clinical laboratory of a pediatric university hospital during a period of 2 months without (n = 80) and subsequently during a period of 1 month with a prototype of an NIR vascular imaging system (n = 45) was conducted. Failure rate (ie, more than 1 puncture) and time of needle manipulation were determined.
Results:
With the NIR vascular imaging system, failure rate decreased from 10/80 to 1/45 (P = .05) and time decreased from 2 seconds (1-10) to 1 second (1-4, P = .07).
Conclusion:
This study showed promising results on the value of an NIR vascular imaging system in facilitating venipunctures.
More Related Videos
Related Concept Videos
Veins of Lower Limbs
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the knee,...
Veins of Upper Limbs
The deep venous system is primarily composed of the ulnar and radial veins. The ulnar vein, which drains the fingers through the superficial palmar venous arches, and the radial vein, which serves the palms via the deep palmar...
Veins as Blood Reservoirs

