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Cardiac surgery in a patient with paroxysmal nocturnal hemoglobinuria
Sharon H L Chu1, David Andrews, Yuki Watanabe
1Department of Cardiothoracic Surgery, Royal Perth Hospital, Perth, Western Australia. sharonchu@gmail.com
Abstract:
A 44-year-old woman, who had been diagnosed with paroxysmal nocturnal hemoglobinuria, presented with chest pain. Angiography revealed critical distal left main stenosis and proximal stenoses of the left anterior descending and circumflex arteries. Prophylactic antibiotics, infusion of blood products and mannitol intraoperatively, and antithrombotic therapy postoperatively ensured a good outcome of coronary artery bypass graft surgery under cardiopulmonary bypass.
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