Related Experiment Video
Updated: Jun 4, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
A case of aspergillosis associated with intralobar pulmonary sequestration
Hiromasa Morikawa1, Toru Tanaka, Masatsugu Hamaji
1Department of General Thoracic Surgery, National Hospital Organization, Nagara Medical Center, Nagara, Gifu, Japan. hiromasa-morikawa@umin.ac.jp
Abstract:
We present a case of intralobar pulmonary sequestration (IPS) and pulmonary aspergillosis (PA) in a 32-year-old Japanese man. Immunological examination indicated an initial diagnosis of PA and an antifungal agent was administered. Since an abnormal chest shadow persisted, another causative lung disease was suspected to exist. Further inspection revealed the presence of IPS and surgical resection was performed. The symptoms of IPS are usually secondary to pyogenic infection; nevertheless, Aspergillus is a possible causative microorganism.
Insights
This case study highlights a rare co-occurrence of intralobar pulmonary sequestration and pulmonary aspergillosis. Diagnosis was challenging, requiring surgical intervention for the sequestration after initial antifungal treatment for aspergillosis.
Area of Science:
- Pulmonology
- Infectious Diseases
- Thoracic Surgery
Background:
- Intralobar pulmonary sequestration (IPS) is a congenital lung malformation.
- Pulmonary aspergillosis (PA) is a fungal infection of the lungs.
- Co-infection of IPS and PA is exceptionally rare.
Related Concept Videos
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Atypical Pneumonia
Pneumonia II: Pathophysiology
Pneumothorax II: Pathophysiology
