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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
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Circulating CD4+CD161+CD196+ Th17 cells are not increased in immune thrombocytopenia

Daria Sollazzo, Sara Trabanelli, Antonio Curti

    Haematologica
    |March 2, 2011
    PubMed
    Abstract

    No abstract available in PubMed .

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    T Cell Types and Functions01:24

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    When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
    Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...

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