Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
Therapeutic Drug Monitoring: Overview and Classification01:16

Therapeutic Drug Monitoring: Overview and Classification

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Medial Dislocation of the Long Head of the Biceps without Concomitant Subscapularis Tear: A Case Report.

Journal of orthopaedic case reports·2020
Same author

Optimization of the racking hitch knot: how many half hitches and which suture material provide the greatest security?

Clinical orthopaedics and related research·2014
Same author

Algorithmic treatment of Kienböck disease; beyond staging.

Techniques in hand & upper extremity surgery·2011
Same journal

Reinsertion of the Extensor Pollicis Brevis for Correction of Z-Deformity in Advanced Thumb Carpometacarpal Osteoarthritis.

Techniques in hand & upper extremity surgery·2026
Same journal

Open-Guided Latarjet With Suture-Button Fixation: Early Experience.

Techniques in hand & upper extremity surgery·2026
Same journal

A Clean Slate.

Techniques in hand & upper extremity surgery·2026
Same journal

The Sandwich Paired Abdominal Flaps Technique for Circumferential Degloving Defects of Digits.

Techniques in hand & upper extremity surgery·2026
Same journal

Double Cerclage Wiring (DCW) of Displaced Stable Olecranon Fractures.

Techniques in hand & upper extremity surgery·2026
Same journal

Dorsal Distal Radius Plate Coverage With the Use of Extensor Retinacular Flap.

Techniques in hand & upper extremity surgery·2026
See all related articles

Related Experiment Video

Updated: Jun 4, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

A classification-based treatment algorithm for Kienböck disease: current and future considerations.

Bradley M Saunders1, David Lichtman

  • 1Department of Orthopaedic Surgery, John Peter Smith Hospital/University of North Texas Health Science Center Fort Worth, TX, USA. bsaunders@jpshealth.org

Techniques in Hand & Upper Extremity Surgery
|March 2, 2011
PubMed
Summary
This summary is machine-generated.

Kienböck disease, a carpal lunate disorder, involves progressive changes. Early diagnosis and intervention, considering biologic factors and advanced imaging, improve outcomes.

Related Experiment Videos

Last Updated: Jun 4, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Area of Science:

  • Orthopedics
  • Hand Surgery
  • Radiology

Background:

  • Kienböck disease is a distinct carpal lunate disorder.
  • It presents with progressive clinical and radiographic changes.
  • Understanding disease progression is key for effective intervention.

Purpose of the Study:

  • To reexamine Kienböck disease classification.
  • To integrate emerging concepts into stage-specific treatment.
  • To highlight advancements in diagnostics and therapeutics.

Main Methods:

  • Review of current literature on Kienböck disease.
  • Analysis of new diagnostic techniques (advanced imaging, arthroscopy).
  • Evaluation of emerging therapeutic strategies (gene/cell-based therapies).

Main Results:

  • Biologic processes, not just trauma, may drive disease.
  • Vascular and cartilaginous changes are critical.
  • Infantile, juvenile, and geriatric forms exhibit unique pathways.

Conclusions:

  • Advanced imaging and arthroscopy aid early diagnosis.
  • Gene and cell therapies show promise for early stages.
  • Updated classification systems are needed to incorporate new findings for tailored, stage-specific treatment.