Psuedomyxoma peritonei secondary to adenocarcinoma of the cecum

Hussah Al-Buainain1, Yasser Al-Jehani, Khaled Moghazy

  • 1Department of Surgery, University of Dammam, Dammam, Kingdom of Saudi Arabia.

Insights

Pseudomyxoma peritonei, a rare condition, often mimics appendicitis. This case highlights a 71-year-old man with cecal adenocarcinoma presenting with pseudomyxoma peritonei symptoms.

Area of Science:

  • Gastroenterology
  • Oncology
  • Surgical Pathology

Background:

  • Pseudomyxoma peritonei (PMP) is a rare, progressive malignancy characterized by mucinous ascites.
  • Patients frequently present with non-specific symptoms, including abdominal distension or acute appendicitis-like presentations.

Observation:

  • A 71-year-old male presented with right iliac fossa pain, fever, and vomiting.
  • Physical examination revealed a palpable right iliac fossa mass, further confirmed by radiological imaging.
  • Diagnostic laparoscopy identified gelatinous material and a right iliac fossa mass, with initial aspirates negative for malignancy.

Findings:

  • Despite initial negative cytology, persistent disease progression necessitated surgical intervention.
  • A right hemicolectomy was performed due to the unrelenting nature of the condition.
  • Histopathological analysis confirmed moderately differentiated adenocarcinoma of the cecum, Duke's C2 staging.

Implications:

  • This case underscores the importance of considering PMP in the differential diagnosis of abdominal masses and appendicitis-like symptoms.
  • Delayed diagnosis and treatment can occur, emphasizing the need for thorough investigation in persistent cases.
  • Accurate histopathological diagnosis is crucial for appropriate staging and management of cecal adenocarcinoma presenting as PMP.

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