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A new solvatochromic fluorophore for exploring nonpolar environments created by biopolymers
Abulfazl Fakhari M1, Steven E Rokita
1Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Abstract:
The fluorescence of a new aminocyanonaphthalene exhibits exquisite sensitivity to its environment and responds to a solvent change from water to hexane with greater than a 100-fold increase in intensity and 100 nm shift in λ(max.em). These properties should support many applications including the detection of abasic sites within duplex DNA as illustrated below.
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