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Updated: Jun 4, 2026
10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Migraine and cardiovascular disease.
1Head of the Merck Investigator Studies Program, Scientific Education Group, Office of the Chief Medical Officer, Merck Inc., Upper Gwynedd, PA, USA. marcelo_bigal@merck.com
Arquivos De Neuro-Psiquiatria
|March 2, 2011
Summary
Migraine is linked to increased risks of brain lesions and broader cardiovascular issues, including heart attack and stroke. This review examines the evidence connecting migraine and cardiovascular disease.
Area of Science:
- Neurology
- Cardiology
- Epidemiology
Background:
- Migraine, particularly with aura, is a known risk factor for ischemic brain lesions.
- Emerging evidence suggests a connection between migraine (with and without aura) and various ischemic vascular disorders.
- These include angina, myocardial infarction, coronary revascularization, claudication, and cardiovascular mortality.
Purpose of the Study:
- To review the association between migraine and cardiovascular disease.
- To present diagnostic criteria and pathophysiology of migraine.
- To summarize existing evidence, including meta-analyses and recent epidemiological studies.
Main Methods:
- Literature review of studies on migraine and cardiovascular disease.
- Summary of diagnostic criteria and pathophysiology of migraine.
- Presentation of findings from a recent meta-analysis and a large epidemiological study.
Main Results:
- Migraine is an established risk factor for ischemic brain lesions.
- Evidence links migraine to a wider spectrum of cardiovascular and vascular disorders.
- Recent meta-analyses and epidemiological studies reinforce this association.
Conclusions:
- Migraine is significantly associated with an increased risk of cardiovascular disease.
- Further research is warranted to understand the underlying mechanisms.
- Clinical awareness of cardiovascular risks in migraine patients is crucial.
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