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Related Experiment Video

Updated: Jun 4, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

Published on: August 13, 2019

Hormonal contraception and cardiovascular system.

Milena Bastos Brito¹, Fernando Nobre, Carolina Sales Vieira

¹Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, SP, Brazil. milenabastos@usp.br

Arquivos Brasileiros De Cardiologia

|March 2, 2011

Summary

This summary is machine-generated.

Hormonal contraceptives are popular for preventing pregnancy but may increase cardiovascular risks. This review examines their impact on blood clots and high blood pressure in women, especially young females.

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Last Updated: Jun 4, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

Published on: August 13, 2019

Area of Science:

Reproductive Health
Cardiovascular Medicine
Pharmacology

Background:

Hormonal contraception is a leading method for pregnancy prevention.
Existing literature suggests a link between hormone therapy and cardiovascular risks.
Cardiovascular diseases are increasingly prevalent in young women.

Purpose of the Study:

To provide updated guidelines on contraceptive choices for women with cardiovascular risk factors.
To review the scientific literature on hormonal contraceptives and cardiovascular health.
To inform clinical practice regarding safe contraception for at-risk populations.

Main Methods:

Comprehensive literature review of recent scientific data.
Analysis of studies focusing on hormonal contraceptives.
Examination of effects on arterial thrombosis, venous thrombosis, and hypertension.

Main Results:

Hormonal contraceptives can influence the risk of arterial and venous thrombosis.
Use of hormonal contraceptives may be associated with elevated systemic blood pressure.
The prevalence of these conditions is rising among young females.

Conclusions:

Careful consideration of cardiovascular risk factors is essential when prescribing hormonal contraceptives.
Further research is needed to refine guidelines for contraception in women with cardiovascular disease risk.
Informing women about potential risks is crucial for shared decision-making.