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Updated: Jun 4, 2026

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Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development
Published on: January 26, 2018
Human myometrial smooth muscle cells and cervical fibroblasts in culture : a comparative study
F Cavaillé1, D Cabrol, F Ferre
1INSERM U., Paris, France.
Methods in Molecular Medicine
|March 2, 2011
Abstract:
Uterine contractility and cervical tonicity change throughout the menstrual cycle and pregnancy in response to modifications in hormonal environment and tissue receptivity to hormones. The uterine wall consists of a smooth muscle (myometrium) organized into three layers. the inner and outer layers, mainly composed of smooth muscle cells, and the richly vascularized intermediate layer The musculature is thick in the corpus uteri and vanishes at the level of the corpus/cervix Junction. The cervix itself is formed mainly by connective tissue.

