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Related Concept Videos

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres
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Genome studies at the PAG 2011 conference.

R Appels1, D L Adelson, P Moolhuijzen

  • 1Centre for Comparative Genomics, Murdoch University, Perth, 6150, WA, Australia. rudiappels5@gmail.com

Functional & Integrative Genomics
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Summary

Advances in plant, animal, and microbe genome studies were presented at the 2011 Plant and Animal Genome meeting. Key research areas included genome dynamics and biological recognition, enhancing our understanding of complex biological systems.

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Area of Science:

  • Genomics
  • Molecular Biology
  • Bioinformatics

Background:

  • The Plant and Animal Genome (PAG) meeting is a key event for researchers in genomics.
  • Understanding complex biological systems requires insights from genome studies.

Purpose of the Study:

  • To summarize plenary lectures from the 2011 PAG meeting.
  • To highlight advances in plant, animal, and microbe genome research.
  • To provide insights into genome dynamics and biological recognition.

Main Methods:

  • Review of plenary lecture content.
  • Focus on major advances in specific research areas.
  • Exclusion of workshops, posters, and technology suppliers.

Main Results:

  • Significant progress in understanding genome change dynamics.
  • New insights into biological recognition processes.
  • Advances impacting the study of complex biological systems.

Conclusions:

  • The 2011 PAG meeting showcased substantial advancements in genome research.
  • These advances are crucial for a deeper comprehension of biological complexity.
  • Future research directions are informed by these genomic insights.