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Anaplastic lymphoma masquerading as sclerosing mesenteritis: a case report
Jay Luther1, Alexander J Faje, Mahmoud Al-Hawary
1Department of Internal Medicine, Division of Gastroenterology, University of Michigan Health System, Ann Arbor, MI 48109-5682, USA.
Introduction:
Sclerosing mesenteritis is a rare fibroinflammatory disease of unknown pathogenesis and etiology. Although more commonly benign in its clinical course, sclerosing mesenteritis can mimic certain malignant disorders, such as lymphoma.
Case Report:
This report describes the case of a previously healthy young woman who develops an acute illness thought to be related to sclerosing mesenteritis following an extensive diagnostic work-up including biopsy sampling, which was negative for malignancy. However, despite aggressive medical care, the patient passed away. Autopsy revealed extensive inflammation secondary to anaplastic lymphoma.
Conclusion:
The case very graphically highlights an important clinical observation that lymphoma can masquerade as sclerosing mesenteritis.