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Updated: Jun 4, 2026
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Multiple bilateral ocular metastases from malignant melanoma associated with blue nevi
Amy T Kelmenson1, Sandeep Grover
1Department of Ophthalmology, University of Florida College of Medicine, Jacksonville, Florida 32209, USA.
Purpose:
Malignant melanoma associated with a blue nevus is a rare diagnosis. Additionally, only a handful of cases of malignant melanoma associated with blue nevi involving the ocular structures have been reported. We report a probable case of malignant melanoma associated with a blue nevus with metastasis to multiple bilateral ocular structures.
Methods:
Observational case report.
Results:
We report a case of a 27-year-old man with lymph node biopsy-proven malignant melanoma as well as a separate skin biopsy of a blue nevus, who developed multiple bilateral pigmented ocular lesions on the sclera, iris, trabecular meshwork, and choroid.
Conclusions:
Although ocular histopathologic evidence could not be obtained, our case likely represents a case of explosive widespread metastasis probably originating from a blue nevus of unknown location, which involved both eyes and adnexae.
