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Updated: Jun 4, 2026

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
Published on: January 10, 2015
[An attempt to rationalize adverse health effects following tobacco smoking]
Krzysztof Szyfter1, Joanna Janiszewska, Kinga Pelińska
1Zakład Mutagenezy Srodowiskowej, Instytut Genetyki Człowieka PAN, Poznań. szyfkris@man.poznan.pl
Abstract:
Statistics concerning tobacco smoking confronted with cancer epidemiology indicates that only a minority of smokers develops terminal cancer. To much extent it could be explained by genetic polymorphism responsible for a variable risk to develop cancer and its further progression. Then, a comparative analysis of the data concerning cancer deaths regarding a decline of smoking in developed countries unravels other factors previously not considered to represent carcinogenic agents. Human papilloma virus (HPV) could serve as an example of such agent exerting adverse health effects once attributed only to tobacco.
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