Conflicts of interest in human subjects research: special considerations for academic emergency physicians

Trust in the doctor-patient or investigator-subject relationship is vital to the practice of medicine and advancement through biomedical research. Individual and environmental factors can make this trust more difficult to establish in the emergency department (ED). To perform research ethically and maintain this trust, it is important to minimize and manage conflicts of interest in human subjects research. While principle-based ethics are an important starting point, the virtue of the individual investigator is required to assure that the interests and safety of research participants are prioritized over the interests of the investigator or the medical community at large. SAEM Ethics Committee 2009-2010 Objective 4: "Based on the results of the didactic session presented at the annual meeting, develop a guide to assist SAEM members in the recognition of potential conflicts of interest in the practice of academic emergency medicine".