Related Experiment Video
Updated: Feb 7, 2026

Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer
Published on: May 18, 2020
On the frontline of screening for breast cancer
1Department of Radiology, Emory University School of Medicine, Atlanta, GA, USA. cdorsi@emory.edu
Abstract:
The mainstay of screening for breast cancer is the mammogram. There are several randomized control trials that demonstrate a significant decrease in breast cancer mortality when compared to women without screening mammography included in their care. Digital mammography has improved detection in the dense breast. With the introduction of digital mammography, other novel techniques such as stereo digital mammography (SDM) and tomosynthesis can reduce recall significantly without a negative effect on cancer detection. Magnetic resonance imaging (MRI) and ultrasound added to mammography can improve cancer detection for high-risk women but can have false positive consequences.
Related Concept Videos
Cancer
Genetic Screens
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
What is Cancer?
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
Cancer Prevention
Some...
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

