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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
Increased left atrial volume index predicts a poor prognosis in patients with heart failure
Harutoshi Tamura1, Tetsu Watanabe, Satoshi Nishiyama
1Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Yamagata, Japan.
Insights
Left atrial volume index (LAVI) can predict cardiac events in heart failure (HF) patients. Higher LAVI indicates increased risk, aiding in patient stratification for better HF management.
Area of Science:
- Cardiology
- Echocardiography
- Heart Failure Research
Background:
- Left atrial volume index (LAVI) reflects left ventricular diastolic dysfunction.
- Prognostic value of LAVI in heart failure (HF) requires further investigation.
Purpose of the Study:
- To investigate the prognostic value of LAVI in patients hospitalized for HF.
- To determine if LAVI can predict cardiac events in HF patients.
Main Methods:
- Transthoracic echocardiography in 146 HF patients.
- Median follow-up of 448 days.
- Cardiac events analyzed using Kaplan-Meier and Cox proportional hazard models.
Main Results:
- Higher LAVI was observed in patients with cardiac events (56 ± 26 vs 44 ± 22 mL/m(2)).
- Elevated LAVI (>53.3 mL/m(2)) correlated with the highest risk of cardiac events.
- High LAVI independently predicted cardiac events (HR 1.427, P < .05).
Conclusions:
- LAVI is a valuable tool for risk stratification in HF patients.
- LAVI can help identify HF patients at higher risk for cardiac events.
Background:
Left atrial volume index (LAVI) is known to reflect the duration and severity of increased left atrial pressure caused by left ventricular (LV) diastolic dysfunction. However, the prognostic value of LAVI in patients with heart failure (HF) has not been fully investigated.
Methods And Results:
Transthoracic echocardiography was performed in 146 consecutive patients (78 men, 68 women; mean age 72 ± 12 y) who were hospitalized for HF. There were 45 cardiac events (32%) during a median follow-up period of 448 days. There were no significant differences in LV end-diastolic dimensions or ejection fraction between patients who did or did not have cardiac events. However, LAVI was markedly higher in patients with, than those without, cardiac events (56 ± 26 vs 44 ± 22 mL/m(2); P < .01). Kaplan-Meier analysis showed that there was a stepwise increase in risk of cardiac events with each increment of LAVI category, and LAVI >53.3 mL/m(2) correlated with the highest risk of cardiac events (log-rank test; P < .01). Multivariate Cox proportional hazard analysis showed that high LAVI was an independent predictor for cardiac events (hazard ratio 1.427; 95% confidence interval 1.024-1.934; P < .05).
Conclusion:
LAVI may be useful for stratification of risk in patients with HF.
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