Increased left atrial volume index predicts a poor prognosis in patients with heart failure

Harutoshi Tamura1, Tetsu Watanabe, Satoshi Nishiyama

  • 1Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Yamagata, Japan.

Insights

Left atrial volume index (LAVI) can predict cardiac events in heart failure (HF) patients. Higher LAVI indicates increased risk, aiding in patient stratification for better HF management.

Area of Science:

  • Cardiology
  • Echocardiography
  • Heart Failure Research

Background:

  • Left atrial volume index (LAVI) reflects left ventricular diastolic dysfunction.
  • Prognostic value of LAVI in heart failure (HF) requires further investigation.

Purpose of the Study:

  • To investigate the prognostic value of LAVI in patients hospitalized for HF.
  • To determine if LAVI can predict cardiac events in HF patients.

Main Methods:

  • Transthoracic echocardiography in 146 HF patients.
  • Median follow-up of 448 days.
  • Cardiac events analyzed using Kaplan-Meier and Cox proportional hazard models.

Main Results:

  • Higher LAVI was observed in patients with cardiac events (56 ± 26 vs 44 ± 22 mL/m(2)).
  • Elevated LAVI (>53.3 mL/m(2)) correlated with the highest risk of cardiac events.
  • High LAVI independently predicted cardiac events (HR 1.427, P < .05).

Conclusions:

  • LAVI is a valuable tool for risk stratification in HF patients.
  • LAVI can help identify HF patients at higher risk for cardiac events.
Abstract

Related Concept Videos

Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...