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PulseCath iVAC 3LTM hemodynamic performance for simple assisted flow.

Lars Niclauss1, Ludwig Karlvon Segesser

  • 1Department of Cardiovascular Surgery, University Hospital CHUV, CH-1011 Lausanne, Switzerland. lars.niclauss@chuv.ch

Interactive Cardiovascular and Thoracic Surgery
|March 3, 2011
PubMed
Summary

The PulseCath iVAC 3L™ left ventricular assist device effectively supports transitory left heart failure post-surgery. Optimal flow rates up to 2.5 L/min were observed at specific frequencies and low afterload.

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Area of Science:

  • Cardiovascular Engineering
  • Biomedical Devices
  • Hemodynamics

Background:

  • Transitory left heart failure or dysfunction is a critical complication post-cardiac surgery.
  • Left ventricular assist devices (LVADs) offer a therapeutic option for such conditions.
  • The PulseCath iVAC 3L™ is designed to provide temporary circulatory support.

Purpose of the Study:

  • To evaluate the in vitro performance of the PulseCath iVAC 3L™ left ventricular assist device.
  • To determine the optimal operating parameters for achieving maximal blood flow.
  • To assess the device's flow characteristics under varying afterload conditions.

Main Methods:

  • An in vitro model was utilized to simulate circulatory conditions.
  • The study examined pump flow rates at different inflation/deflation frequencies.
  • Afterload was systematically varied to assess its impact on device performance.

Main Results:

  • Optimal pump flow was achieved at inflation/deflation frequencies between 70-80/min.
  • The maximal flow rate recorded was approximately 2.5 L/min at a minimal afterload of 22 mmHg.
  • Increasing afterload up to 66 mmHg resulted in a limitation of flow rate and cardiac support.

Conclusions:

  • The PulseCath iVAC 3L™ demonstrates effective temporary circulatory support in vitro.
  • Device performance is sensitive to operating frequency and afterload conditions.
  • The device's ease of handling, connected to a standard console, is advantageous.