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Published on: December 9, 2022
Thrombovascular events affect quality of life in patients with systemic lupus erythematosus
Amaris K Balitsky1, Valentina Peeva, Jiandong Su
1Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Objective:
To compare health-related quality of life (HRQOL) of patients with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) with and without previous thrombovascular events (TE).
Methods:
The Medical Outcomes Study Short-Form 36 (SF-36) was used to assess HRQOL in 5 patient groups: (1) primary APS (PAPS; n = 35); (2) APS associated to SLE (SAPS; n = 37); (3) SLE+TE without persistent positive antiphospholipid antibody (SLE+TE-aPL; n = 75); (4) SLE-TE+aPL (n = 71); and (5) SLE-TE-aPL (n = 608).
Results:
The data on both mental component summary and physical component summary (PCS) scores showed an impaired quality of life in all patient groups. Patients in the SLE+TE-aPL group had a lower PCS score compared to patients in the SLE-TE+aPL group.
Conclusion:
The combination of SLE and TE has a more negative influence on reported HRQOL, compared to having SLE or APS alone.
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