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Updated: Aug 8, 2026

From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia
Published on: October 19, 2014
[Trichocellular leukemia. I. Diagnostic significance of membrane markers on tricholeukocytes]
1Ustav hematologie a krevní transfúze, Praha.
Abstract:
On tricholeucocytes (hairy cells) separated from peripheral blood and bone marrow of patients with trichocellular leukaemia the author detected by means of monoclonal antibodies, using the indirect immunofluorescence method, membrane phenotypes. From the results it may be concluded that tricholeucocytes from all examined 19 specimens had membrane phenotypes (mIg, HLA-D, CD 19, CD 20, CD 22) typical for some cells of the B lymphoid series. Moreover, on tricholeucocytes also antigens typical for the monocytic series (CD 11a, CD 11b) were found and some general leucocytic antigens (CD 43 and CD 45).
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